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EBNA1 and Epstein-Barr Virus Associated Tumours by Lori Frappier (auth.) is a nonfiction available to read on EtoBox.

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EBNA1 and Epstein-Barr Virus Associated Tumours 3 Preface 5 Contents 6 1 Introduction 7 References 8 2 Roles of EBNA1 at EBV Episomes 9 2.1 Replication of EBV Episomes 9 2.2 Segregation of EBV Episomes 13 2.3 Activation of EBV Transcription 16 References 18 3 EBNA1-DNA Interactions 25 3.1 Mechanism of EBNA1 Interaction with EBV DNA 25 3.2 Interactions with Cellular DNA 27 References 29 4 EBNA1 Contributions to EBV-Associated Tumours 32 4.1 B Cell Lymphomas 32 4.2 Nasopharyngeal Carcinoma 34 4.3 Gastric Carcinoma 35 References 35 5 Cellular Effects of EBNA1 38 5.1 p53 Regulation 38 5.2 Disruption of PML Nuclear Bodies 40 5.3 Alteration of Signalling 42 5.4 Induction of Oxidative Stress 43 5.5 Induction of Survivin 44 5.6 Modulation of NM23-H1 44 References 45 6 Conclusion 48

Who reads EBNA1 and Epstein-Barr Virus Associated Tumours?

Author

Lori Frappier (auth.)

Publisher

Springer

Published

2013

Language

EN

Category

nonfiction