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Can I read Defining the carbohydrate specificities of Abrus precatorius agglutinin as T (Gal beta 1—-3GalNAc) greater than I/II (Gal beta 1—-3/4GlcNAc). on EtoBox?
Defining the carbohydrate specificities of Abrus precatorius agglutinin as T (Gal beta 1—-3GalNAc) greater than I/II (Gal beta 1—-3/4GlcNAc). by A.M. Wu; S.R. Lin; L.K. Chin; L.P. Chow; J.Y. Lin is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Defining the carbohydrate specificities of Abrus precatorius agglutinin as T (Gal beta 1—-3GalNAc) greater than I/II (Gal beta 1—-3/4GlcNAc). about?
The combining site of the nontoxic carbohydrate binding protein (Abrus precatorius agglutinin, APA) purified from the needs of Abrus precatorius (Jequirity bean), was studied by quantitative precipitin and precipitin-inhibition assays. Of 26 glycoproteins and polysaccharides tested, all, except sialic acid-containing glycoproteins and desialized ovine salivary glycoproteins, reacted strongly with the lectin, and precipitated over 70% of the lectin added, indicating that APA has a broad range of affinity and recognizes (internal) Gal beta 1----sequences of carbohydrate chains. The strong reaction with desialized porcine and rat salivary glycoproteins as well as pneumococcus type XIV polysaccharide suggests that APA has affinity for one or more of the following carbohydrate sequences: Thomsen-Friedenreich (T, Gal beta 1----3GalNAc), blood group precursor type I and/or type II (Gal beta 1----3/4GlcNAc) disaccharide determinants of complex carbohydrates. Among the oligosaccharides tested, the T structure was the best inhibitor; it was 2.4 and 3.2 times more active than type II and type I sequences, respectively. The blood group I Ma-active trisaccharide, Gal beta 1----4GlcNAc beta 1---
Who reads Defining the carbohydrate specificities of Abrus precatorius agglutinin as T (Gal beta 1—-3GalNAc) greater than I/II (Gal beta 1—-3/4GlcNAc).?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- A.M. Wu; S.R. Lin; L.K. Chin; L.P. Chow; J.Y. Lin
- Publisher
- Elsevier BV
- Published
- 1992
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)
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