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Efficacy of Dietary Polyphenols from Whole Foods and Purified Food Polyphenol Extracts in Optimizing Cardiometabolic Health: A Meta-Analysis of Randomized Controlled Trials by Tonny Kiyimba; Peter Yiga; Michael Bamuwamye; Patrick Ogwok; Bart Van der Schueren; Christophe Matthys is a Medicine article available to read on EtoBox.
What is Efficacy of Dietary Polyphenols from Whole Foods and Purified Food Polyphenol Extracts in Optimizing Cardiometabolic Health: A Meta-Analysis of Randomized Controlled Trials about?
The evidence from clinical trials concerning the efficacy of dietary polyphenols on cardiometabolic health is divergent. Therefore, this review aimed to determine the pooled effect of dietary polyphenols on cardiometabolic risk markers and compare the difference in efficacy between whole polyphenol-rich foods and purified food polyphenol extracts. We conducted a random-effect model meta-analysis of randomized controlled trials (RCTs) on the effect of polyphenols on blood pressure, lipid profile, flow-mediated dilation (FMD), fasting blood glucose (FBG), waist circumference, and markers of inflammation. Effect size was expressed as weighted mean difference and 95% CI. RCTs published in English between 2000 and 2021 involving adult participants with cardiometabolic risks were searched in electronic databases. Forty-six RCTs involving 2494 participants with a mean age of 53.3 ±10 y were included in this review. Whole polyphenol-rich food but not purified food polyphenol extracts significantly reduced systolic blood pressure (SBP, −3.69 mmHg; 95% CI: −4.24, −3.15 mmHg; __P__ = 0.00001) and diastolic blood pressure (DBP, −1.44 mmHg; 95% CI: −2.56, −0.31 mmHg; P = 0.0002). Concerning wai
Who reads Efficacy of Dietary Polyphenols from Whole Foods and Purified Food Polyphenol Extracts in Optimizing Cardiometabolic Health: A Meta-Analysis of Randomized Controlled Trials?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Tonny Kiyimba; Peter Yiga; Michael Bamuwamye; Patrick Ogwok; Bart Van der Schueren; Christophe Matthys
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)