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Adult Soft Tissue Sarcoma by G. Bruce Mann; Jonathan J. Lewis; Murray F. Brennan is a Medicine article available to read on EtoBox.

What is Adult Soft Tissue Sarcoma about?

Background: Soft tissue sarcomas (STS) are a group of anatomically and histologically diverse tumours. They account for about 1% of adult malignancies, and about 50% of patients diagnosed with sarcoma eventually die of the disease. These tumours are grouped together because of shared biological characteristics and treatment responses. Methods: A review of the key literature on STS was undertaken, complemented by data taken from the prospectively accumulated database of 3442 patients treated for STS at Memorial Sloan‐Kettering Cancer Center (MSKCC) from July 1982 to December 1997. Results: Despite advances in knowledge of the molecular genetics of STS, the aetiology in most cases remains elusive. Management has been gradually refined over the last two decades. Core biopsy usually provides enough material for diagnosis. Computed tomography and magnetic resonance imaging provide a similar amount of information, which is usually adequate for surgical planning. Amputation as standard treatment for extremity lesions has been replaced by limb‐sparing surgery in about 90% of patients. The role of adjuvant radiation has been further defined: it has been shown to be unnecessary for completel

Who reads Adult Soft Tissue Sarcoma?

Author

G. Bruce Mann; Jonathan J. Lewis; Murray F. Brennan

Publisher

John Wiley and Sons; Blackwell Publishing; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1445-1433)

Published

1999

Language

EN

Field

Medicine (Health Sciences)