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Postbiotics—A Step Beyond Pre- and Probiotics by Jakub Żółkiewicz; Aleksandra Marzec; Marek Ruszczyński; Wojciech Feleszko is a Medicine article available to read on EtoBox.

What is Postbiotics—A Step Beyond Pre- and Probiotics about?

As an imbalance in the intestinal microbiota can lead to the development of several diseases (e.g., type 1 diabetes, cancer, among others), the use of prebiotics, probiotics, and postbiotics to alter the gut microbiome has attracted recent interest. Postbiotics include any substance released by or produced through the metabolic activity of the microorganism, which exerts a beneficial effect on the host, directly or indirectly. As postbiotics do not contain live microorganisms, the risks associated with their intake are minimized. Here, we provided a critical review of postbiotics described in the literature, including their mechanisms of action, clinical characteristics, and potential therapeutic applications. We detailed the pleiotropic effects of postbiotics, including their immunomodulatory, anti-inflammatory, antioxidant, and anti-cancer properties. Although the use of postbiotics is an attractive strategy for altering the microbiome, further study into its efficacy and safety is warranted.

Who reads Postbiotics—A Step Beyond Pre- and Probiotics?

Author

Jakub Żółkiewicz; Aleksandra Marzec; Marek Ruszczyński; Wojciech Feleszko

Publisher

MDPI AG

Published

2020

Language

EN

Field

Medicine (Health Sciences)