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Can I read Deconvoluting Global Cytokine Signaling Networks in Natural Killer Cells on EtoBox?
Deconvoluting Global Cytokine Signaling Networks in Natural Killer Cells by Gabriela M. Wiedemann; Endi K. Santosa; Simon Grassmann; Sam Sheppard; Jean-Benoît Le Luduec; Nicholas M. Adams; Celeste Dang; Katharine C. Hsu; Joseph C. Sun; Colleen M. Lau is a Immunology and Microbiology article available to read on EtoBox.
What is Deconvoluting Global Cytokine Signaling Networks in Natural Killer Cells about?
Results Cytokines peak early during infection. Because cytokine signaling is crucial for NK cell responses during MCMV infection, we profiled the cytokine milieu over the course of infection in spleen, peripheral blood and liver, known sites of active viral replication. In general, all cytokines peaked between days 1 and 2 (D1 and D2) post-infection (PI), which varied between tissues and in persistence (Fig. and Extended Data Fig. ). IFN-α, IL-12p70 and IL-18 all peaked at D2 PI in spleen and blood (Fig. ), but peaked on D1 PI in liver (Extended Data Fig. ). In contrast, IL-2 and IL-15 consistently peaked at D1 PI, but remained elevated in both spleen and blood until at least D2 PI (Fig. ). Although the majority of the
Who reads Deconvoluting Global Cytokine Signaling Networks in Natural Killer Cells?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- Gabriela M. Wiedemann; Endi K. Santosa; Simon Grassmann; Sam Sheppard; Jean-Benoît Le Luduec; Nicholas M. Adams; Celeste Dang; Katharine C. Hsu; Joseph C. Sun; Colleen M. Lau
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)