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What is Bioequivalence of Paliperidone ER Formulations about?

This study evaluated the bioequivalence of two extended release paliperidone formulations for the treatment of schizophrenia. Eighty healthy males were randomly assigned to receive either a single 15 mg tablet of the final formulation or multiple tablets totaling 15 mg of the investigational formulation, with a washout period between. Blood samples were taken to analyze paliperidone levels. The average maximum concentration and total exposure were similar between formulations. The point estimates for compar

Author

Sadia Amin

Language

EN