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Principles of EC50, ED50, pD2 and pA2 Values of Drugs by Avinash Arivazhahan is a book available to read on EtoBox.

What is Principles of EC50, ED50, pD2 and pA2 Values of Drugs about?

The effects of most drugs depend on the dose that is provided to the subject. In line with this, we have a concept called "dose descriptors", which takes into account the relationship between a particular dose of a drug and the corresponding effect produced by it. The commonly used "dose descriptors" include EC 50 (half maximal effective concentration), LC 50 (median lethal concentration), ED 50 (median effective dose), TD 50 (median toxic dose), LD 50 (median lethal dose), etc. This chapter attempts to elucidate the basics of these determinants. In addition, we will also look at the drug toxicity studies that are commonly performed for any new drug.

Author

Avinash Arivazhahan

Publisher

Springer Nature Singapore Pte Ltd Fka Springer Science + Business Media Singapore Pte Ltd

Published

2022

Language

EN

ISBN

9789811953422

Subjects

Science, Philosophy, Chemistry