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Emphysema is characterized by the permanent dilation of air spaces and destruction of their walls, often due to an imbalance between proteases and antiproteases. Factors such as inflammation and smoking can increase protease activity, while conditions like alpha-1 antitrypsin deficiency can decrease antiprotease activity, leading to lung damage. Morphologically, emphysema presents with voluminous, pale lungs and can feature subpleural bullae and blebs, which are air-filled structures resulting from ruptured
- Author
- bhanuja.singh
- Language
- EN