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Clinical Application of a Model-based Cardiac Stroke Volume Estimation Method by Smith, Rachel (author);Balmer, Joel (author);Pretty, Christopher G. (author);Shaw, Geoffrey M. (author);Chase, J. Geoffrey (author) is a Engineering article available to read on EtoBox.

What is Clinical Application of a Model-based Cardiac Stroke Volume Estimation Method about?

A system is needed for monitoring stroke volume (SV) and cardiac output (CO) in unstable patients which is non-additionally invasive, reproducible and reliable in a variety of physiological states. This study evaluates SV estimation accuracy of a non-additionally invasive pulse contour analysis method implemented using a 3-element Windkessel model. The model lumps the properties of the arterial system into 3 parameters: characteristic impedance of the proximal aorta (Z ), and resistance (R) and compliance (C ) of the systemic arteries. Parameter products ZC and RC are dynamically identified from measured femoral arterial pressure waveforms, and Z is a static parameter obtained by calibration. The accuracy of the model is evaluated for a cohort of 9 liver transplant patients, using thermodilution as a reference method. Data were obtained from Vital Data Bank (VitalDB). The study thus provides independent assessment of a pulse contour analysis, proven in animal studies, in an uncontrolled clinical environment. The model tracked trends in SV well over the course of the surgery. However, the 95% range for percentage error was -88% to +53%, outside acceptable limits of ±45%. Main areas

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Author

Smith, Rachel (author);Balmer, Joel (author);Pretty, Christopher G. (author);Shaw, Geoffrey M. (author);Chase, J. Geoffrey (author)

Publisher

Elsevier BV

Published

2020

Language

EN

Field

Engineering (Physical Sciences)