Can I read REM Sleep Behavior Disorder Associated with Parkinson’s Disease and Multiple System Atrophy on EtoBox?

REM Sleep Behavior Disorder Associated with Parkinson’s Disease and Multiple System Atrophy by Schenck, Carlos H.; Högl, Birgit; Videnovic, Aleksandar is a scholarly article available to read on EtoBox.

What is REM Sleep Behavior Disorder Associated with Parkinson’s Disease and Multiple System Atrophy about?

This book describes a sleep disorder belonging to the category of parasomnias (i.e. the sleep behavioral and experiential disorders) characterized by abnormal vocal and motor behaviors in the context of vivid dreams and loss of the customary muscle atonia during the stage of sleep called REM sleep. REM-atonia - one of the defining features of REM sleep, along with rapid-eye-movements and a highly activated brain state - serves a protective function, preventing the dreamer from acting-out dreams and becoming injured. REM sleep behavior disorder (RBD) was first described in 1986 by Schenck and colleagues; since then the understanding of the condition has increased exponentially, also pointing out its strong association with the development of neurodegenerative disorders characterized by alpha synuclein deposition, such as Parkinson's disease, Dementia with Lewy bodies, and Multiple System Atrophy. Furthermore, RBD is now considered one of the earliest markers of ongoing alpha synuclein neurodegeneration, and provides a window of opportunity for testing disease modifying therapies that may slow down or halt the progression of these disorders for which there is currently no cure. Addit

Author

Schenck, Carlos H.; Högl, Birgit; Videnovic, Aleksandar

Publisher

Springer International Publishing : Imprint: Springer

Published

2019

Language

EN

ISBN

9783319901510