Opening book details…
Can I read Neoadjuvant GTX Chemotherapy and IMRT-based chemoradiation for borderline resectable pancreatic cancer on EtoBox?
Neoadjuvant GTX Chemotherapy and IMRT-based chemoradiation for borderline resectable pancreatic cancer by Manish Patel; Sarah Hoffe; Mokenge Malafa; Pamela Hodul; Jason Klapman; Barbara Centeno; Jongphil Kim; James Helm; Tiffany Valone; Gregory Springett is a Medicine article available to read on EtoBox.
What is Neoadjuvant GTX Chemotherapy and IMRT-based chemoradiation for borderline resectable pancreatic cancer about?
## Abstract ## Background and Objectives To improve the likelihood of achieving a margin‐free resection, neoadjuvant induction chemotherapy with GTX (gemcitabine, docetaxel, and capecitabine) followed by 5‐FU‐IMRT was administered to patients with borderline resectable pancreatic cancer. The utility of computed tomography (CT), endoscopic ultrasound (EUS), positron emission tomography (PET), and CA 19‐9 during diagnostic workup and assessment of response was also examined. ## Methods Seventeen patients with borderline resectable pancreatic cancer received a median of three cycles of neoadjuvant GTX induction chemotherapy followed by 5‐FU‐IMRT with dose painting. CA 19‐9, CT mass size, and PET SUV were examined before and after neoadjuvant treatment. ## Results Diagnostic EUS and CT scans displayed similar mean mass sizes and extent of vascular involvement. Eight of the 17 patients achieved an R0 resection. Median CA 19‐9 levels, CT mass size, and PET SUV all significantly decreased after neoadjuvant therapy. The median progression‐free survival and overall survival were 10.48 and 15.64 months, respectively. Six patients are still alive. ## Conclusions Neoadjuvant GTX induction chem
Who reads Neoadjuvant GTX Chemotherapy and IMRT-based chemoradiation for borderline resectable pancreatic cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Manish Patel; Sarah Hoffe; Mokenge Malafa; Pamela Hodul; Jason Klapman; Barbara Centeno; Jongphil Kim; James Helm; Tiffany Valone; Gregory Springett
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-4790)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)