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Is chocolate consumption associated with health outcomes? An umbrella review of systematic reviews and meta-analyses by Nicola Veronese; Jacopo Demurtas; Stefano Celotto; Maria Gabriella Caruso; Stefania Maggi; Francesco Bolzetta; Joseph Firth; Lee Smith; Patricia Schofield; Ai Koyanagi; Lin Yang; Marco Solmi; Brendon Stubbs is a Medicine article available to read on EtoBox.
What is Is chocolate consumption associated with health outcomes? An umbrella review of systematic reviews and meta-analyses about?
Background & aims: The literature regarding the potential health benefits of chocolate consumption are unclear and the epidemiological credibility has not been systematically scrutinized, while the strength of the evidence is undetermined. We therefore aimed to map and grade the diverse health outcomes associated with chocolate consumption using an umbrella review of systematic reviews. Methods: Umbrella review of systematic reviews of observational and interventional studies (randomized placebo-controlled trials, RCTs). For each association, random-effects summary effect size, 95% confidence interval, and 95% prediction interval were estimated. We also assessed heterogeneity, evidence for small-study effect and evidence for excess significance bias. For significant outcomes of the RCTs, the GRADE assessment was furtherly used. Results: From 240 articles returned, 10 systematic reviews were included (8 of which included a metaanalysis), including a total of 84 studies (36 prospective observational studies and 48 interventional). Nineteen different outcomes were included. Among observational studies, including a total of 1,061,637 participants, the best available evidence suggests t
Who reads Is chocolate consumption associated with health outcomes? An umbrella review of systematic reviews and meta-analyses?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Nicola Veronese; Jacopo Demurtas; Stefano Celotto; Maria Gabriella Caruso; Stefania Maggi; Francesco Bolzetta; Joseph Firth; Lee Smith; Patricia Schofield; Ai Koyanagi; Lin Yang; Marco Solmi; Brendon Stubbs
- Publisher
- Elsevier Science; Elsevier ; Churchill Livingstone; Elsevier BV (ISSN 0261-5614)
- Published
- 2018
- Language
- EN
- Field
- Medicine (Health Sciences)