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Correspondence Between Forced Oscillation and Body Plethysmography During Bronchoprovocation with Carbachol in Children by Dr. Wernfrid Buhr; Rudolf Jörres; Dietrich Berdel; Ferenc J. Làndsér is a Medicine article available to read on EtoBox.

What is Correspondence Between Forced Oscillation and Body Plethysmography During Bronchoprovocation with Carbachol in Children about?

## Abstract We compared dose–response curves obtained with the forced oscillation technique (FOT) and with body plethysmography during bronchoprovocation in children. In 40 stable asthmatic children (age, 5–16 yr) we performed challenges with doubling concentrations of inhaled carbachol (0.15–10 mg/mL) until specific airway resistance SRaw had increased by 100% (PC~100~SRaw). The FOT‐response was assessed by total respiratory system resistance (Rrs, cmH~2~O·1^−1^·s) and reactance (Xrs, cmH~2~O·1^−1^·s) from 8 to 26 Hz, expressed as mean Rrs (Rrs), mean Xrs (Xrs), Rrs at 8 Hz (Rrs~8~), and mean slope of Rrs (dRrs/df). Dose–response curves were analyzed for threshold concentrations (TC) causing a 3 SD change from baseline and sensitivity indices (SI) defined as differences between baseline and postchallenge values (at PC~100~SRaw) divided by baseline SD. Median TC of Rrs~8~, Rrs, Xrs, dRrs/df, and SRaw was 0.21, 0.30, 0.34, 0.41, and 0.42 mg/mL, respectively, indicating a slightly higher sensitivity for FOT. Median SI values of SRaw and Xrs (12.0 and 8.2; difference n.s.) were significantly higher than those of the other parameters. Multiple regression analysis revealed only the abso

Who reads Correspondence Between Forced Oscillation and Body Plethysmography During Bronchoprovocation with Carbachol in Children?

Author

Dr. Wernfrid Buhr; Rudolf Jörres; Dietrich Berdel; Ferenc J. Làndsér

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 8755-6863)

Published

1990

Language

EN

Field

Medicine (Health Sciences)