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Can I read FORGE: A Novel Scoring System to Predict the MIB-1 Labeling Index in Intracranial Meningiomas on EtoBox?

FORGE: A Novel Scoring System to Predict the MIB-1 Labeling Index in Intracranial Meningiomas by Wach, Johannes (author);Lampmann, Tim (author);Güresir, Ági (author);Schuss, Patrick (author);Vatter, Hartmut (author);Herrlinger, Ulrich (author);Becker, Albert (author);Hölzel, Michael (author);Toma, Marieta (author);Güresir, Erdem (author) is a Medicine article available to read on EtoBox.

What is FORGE: A Novel Scoring System to Predict the MIB-1 Labeling Index in Intracranial Meningiomas about?

## Simple Summary Meningiomas are predominantly benign intracranial tumors, and surgical therapy represents the treatment of choice. However, the risk of recurrence and scheduling of follow-up intervals are significantly influenced by immunohistochemical items such as the MIB-1 labeling index. To date, it is not possible to integrate this essential information into the pre- or intraoperative surgical decision making. In the present study, we therefore analyzed baseline variables associated with the MIB-1 labeling index. We found four easily identifiable and routinely recorded risk factors for an increased MIB-1 index and developed a simple and quick-to-use score that allows us to estimate the risk of an elevated MIB-1 index prior to the surgical resection. Furthermore, this score seems to predict the progression-free survival in intracranial meningiomas. We believe that this score might us to more reliably guide patients in preoperative surgical strategy planning and postoperative follow-up scheduling. ## Abstract The MIB-1 index is an essential predictor of progression-free-survival (PFS) in meningioma. To date, the MIB-1 index is not available in preoperative treatment planning.

Who reads FORGE: A Novel Scoring System to Predict the MIB-1 Labeling Index in Intracranial Meningiomas?

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Author
Wach, Johannes (author);Lampmann, Tim (author);Güresir, Ági (author);Schuss, Patrick (author);Vatter, Hartmut (author);Herrlinger, Ulrich (author);Becker, Albert (author);Hölzel, Michael (author);Toma, Marieta (author);Güresir, Erdem (author)
Publisher
MDPI AG
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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