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Fertility issues and pregnancy outcomes in Turner syndrome by Matilde Calanchini; Christina Y.L. Aye; Elizabeth Orchard; Kathy Baker; Tim Child; Andrea Fabbri; Lucy Mackillop; Helen E. Turner is a Medicine article available to read on EtoBox.

What is Fertility issues and pregnancy outcomes in Turner syndrome about?

## Objective: To study fertility issues and pregnancy outcomes in turner syndrome (ts). ## Design: Retrospective cohort study. ## Setting: Not applicable. ## Patient(s): One hundred fifty-six ts patients, median age 32 years, 23 mosaic 45,x/46,xx, 45,x/47,xxx, 45,x/46,xx/47,xxx. ## Intervention(s): None. ## Main outcome measure(s): Fertility choices, spontaneous pregnancy, and oocyte donation (od) outcomes. conditions associated with aortic dissection and poor pregnancy outcomes at preconception were considered. pregnancy-related aortic dimension changes and the long-term impact of pregnancy on ts-related comorbidities were assessed. ## Results(s): In all, 13.5% had spontaneous pregnancies, resulting in a pregnancy with live birth in 18 patients (37 newborns); 16% considered od, one adopted, and one underwent fertility preservation. spontaneous pregnancy predictive factors were a karyotype with a second or third cell line with more than one x and spontaneous menarche. in all, 47.6% had miscarriages, two experienced preeclampsia, and two had gestational diabetes. one daughter was diagnosed with ts in adulthood. seven of 14 who attempted od had a pregnancy with live birth; two of sev

Who reads Fertility issues and pregnancy outcomes in Turner syndrome?

Author

Matilde Calanchini; Christina Y.L. Aye; Elizabeth Orchard; Kathy Baker; Tim Child; Andrea Fabbri; Lucy Mackillop; Helen E. Turner

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1556-5653)

Published

2020

Language

EN

Field

Medicine (Health Sciences)