Opening book details…
Can I read Quantitative Determination of Almitrine in Plasma by High-performance Liquid Chromatography on EtoBox?
Quantitative Determination of Almitrine in Plasma by High-performance Liquid Chromatography by George W. Parkhurst; Norbert Bromet; Catherine MacLeod; Romeo T. Bachand Jr.; Paul E. Carson is a Chemistry article available to read on EtoBox.
What is Quantitative Determination of Almitrine in Plasma by High-performance Liquid Chromatography about?
Almitrine (I) is a new peripheral chemoreceptor [l, 21 agonist for treatment of hypoxia and/or hypercapnia which improves ventilation perfusion inequality [3--51. AImitrine is currently under phase II investigation in the U.S.A. for use in chronic obstructive lung disease in studies sponsored by the Amaric Corporation, Mentor, OH, U.S.A. This drug also has potential usefulness in other conditions in which oxygen delivery is impaired. Studies of the pharmacokinetics of ahnitrine require a separation system with high selectivity and high sensitivity because of the minor chemical differences between almitrine and those of endogenous compounds. This paper presents a method for the separation, detection and quantitation of ahnitrine by reversed-phase high-performance liquid chromatography (HPLC). The
Who reads Quantitative Determination of Almitrine in Plasma by High-performance Liquid Chromatography?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- George W. Parkhurst; Norbert Bromet; Catherine MacLeod; Romeo T. Bachand Jr.; Paul E. Carson
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0378-4347)
- Published
- 1983
- Language
- EN
- Field
- Chemistry (Physical Sciences)