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Incidence, risk factors, treatment, and survival of ovarian metastases of colorectal origin: a Dutch population-based study by Bakkers, C.; van der Meer, R.; Roumen, R. M.; Lurvink, R. J.; Lemmens, V. E.; van Erning, F. N.; de Hingh, I. H. is a Medicine article available to read on EtoBox.

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## Objective: The aim of this nationwide study was to provide insight in the incidence, risk factors, treatment, and survival of patients with ovarian metastases from colorectal cancer (crc). ## Methods: Data from the netherlands cancer registry were used. all newly diagnosed female crc patients between 2008 and 2016 were included. treatment was categorized as follows: cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (crs-hipec); resection of the primary tumor; palliative treatment; and no treatment. overall survival (os) was investigated using kaplan-meier and multivariable cox regression analyses. ## Results: Of 53,883 female crc patients, 11,343 (21.1%) had metastases at time of diagnosis. among them, 471 (4.2%) had ovarian metastases. within latter group, 27.2% received crs-hipec; 38.4% underwent resection of the primary tumor; 25.3% received palliative treatment; and 9.1% received no treatment. median os of all patients with ovarian metastases was 17.5 months. in patients receiving crs-hipec, os was significantly longer than in patients undergoing resection only (median os 34.1 vs. 17.5 months, adjusted hr 0.44 [0.33-0.66]). five-year os was 28.5% fo

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Author

Bakkers, C.; van der Meer, R.; Roumen, R. M.; Lurvink, R. J.; Lemmens, V. E.; van Erning, F. N.; de Hingh, I. H.

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0179-1958)

Published

2020

Language

EN

Field

Medicine (Health Sciences)