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Can I read Antioxidant Power of Angiotensin-converting Enzyme Inhibitors in Vitro on EtoBox?
Antioxidant Power of Angiotensin-converting Enzyme Inhibitors in Vitro by Iris F. F. Benzie; Brian Tomlinson is a Medicine article available to read on EtoBox.
What is Antioxidant Power of Angiotensin-converting Enzyme Inhibitors in Vitro about?
__Aims__ There is controversy regarding the potential antioxidant effect of captopril, therefore this study was performed to compare the __in vitro__ antioxidant power of captopril with other angiotensin‐converting enzyme (ACE) inhibitors. __Methods__ Antioxidant power of captopril, enalapril, fosinopril, perindopril, quinapril and ramipril in aqueous solution was measured using the ferric reducing (antioxidant) power (FRAP) assay; captopril was also measured in ethanolic solution. __Results__ Only captopril showed significant antioxidant power, demonstrating a stoichiometric factor of 1.0 in this assay. Concentration‐related antioxidant power was seen in both aqueous and ethanolic solutions. __Conclusions__ Captopril shows antioxidant activity __in vitro__. This property could be relevant __in vivo__ if captopril is concentrated in membranes, lipoproteins or at other important sites.
Who reads Antioxidant Power of Angiotensin-converting Enzyme Inhibitors in Vitro?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Iris F. F. Benzie; Brian Tomlinson
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0306-5251)
- Published
- 1998
- Language
- EN
- Field
- Medicine (Health Sciences)