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The study investigates the effects of luteoloside, a flavonoid from Gentiana macrophylla, on non-small cell lung cancer (NSCLC) cells, revealing that it induces G0/G1 phase arrest and promotes autophagy through the ROS-mediated AKT/mTOR/p70S6K signaling pathway. Luteoloside effectively inhibits cancer cell proliferation while not significantly inducing apoptosis, suggesting a non-apoptotic cell death mechanism. The findings highlight luteoloside

Author

udaya.singh

Language

EN