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Radiation Therapy Alone for Imaging-Defined Meningiomas by Mariam P. Korah; Adam W. Nowlan; Peter A.S. Johnstone; Ian R. Crocker is a Medicine article available to read on EtoBox.

What is Radiation Therapy Alone for Imaging-Defined Meningiomas about?

Purpose: To assess local control and treatment-related toxicity of single-modality radiation therapy (RT) in the treatment of imaging-defined meningiomas. Methods and Materials: The records of Emory University School of Medicine, Atlanta, GA, were reviewed between 1985 and 2003. We identified 41 patients with 42 meningiomas treated with RT alone for lesions diagnosed on imaging alone. No patients received a histologic diagnosis. Patients in whom there was uniform agreement that the tumor represented a meningioma were accepted for therapy. Of the patients, 22 were treated with stereotactic radiosurgery (SRS), 11 with fractionated stereotactic radiotherapy (FSR), and 9 with three-dimensional conformal therapy (3DCRT). The median doses of SRS, FSR, and 3DCRT were 14 Gy, 50.4 Gy, and 52.2 Gy, respectively. Results: Median follow-up was 60 months. Of 42 meningiomas, 39 were locally controlled. The 8-year actuarial local control rate by Kaplan-Meier methods was 94%. One failure occurred 6 months after 3DCRT, a second at 34 months after FSR, and a third at 125 months after SRS. A temporary symptomatic radiation-related neurologic sequela developed in 1 patient treated with SRS. No fatal t

Who reads Radiation Therapy Alone for Imaging-Defined Meningiomas?

Author

Mariam P. Korah; Adam W. Nowlan; Peter A.S. Johnstone; Ian R. Crocker

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2010

Language

EN

Field

Medicine (Health Sciences)