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Safety, Efficacy, and Cost-effectiveness of Outpatient Surgery for Uncomplicated Acute Appendicitis. The PENDI-CSI Randomized Clinical Trial by Virgina Durán Muñoz-Cruzado; Laura Navarro Morales; Felipe Pareja Ciuró; Daniel Aparicio Sánchez; Luis Tallón Aguilar; Javier Padillo-Ruiz is a Medicine article available to read on EtoBox.

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## Objective: To evaluate the safety, efficacy, and cost-effectiveness of outpatient appendectomy in patients with uncomplicated acute appendicitis. ## Summary Background Data: Given that acute appendicitis is the most common cause of acute abdomen, the introduction of outpatient appendectomy protocols could significantly improve the effectiveness and sustainability of healthcare systems. ## Methods: A total of 300 patients were enrolled from October 2018 to June 2021 in the PENDI-CSI randomized clinical trial:149 were assigned to the outpatient surgery group (OPS) and 151 to the inpatient surgery group (IPS), followed by one month postoperatively. All patients were aged > 14 years and had uncomplicated acute appendicitis. Exclusion criteria were pregnancy, neoplasms, inflammatory bowel disease, and high anesthetic risk (ASA IV). The OPS group was discharged from the post-anesthesia care unit while the IPS group was admitted. ## Results: In total, 128 patients in the OPS group (85.9%) were discharged without admission. Predictors whether patients in the OPS group had to be admitted were aged over 31 years [RR 2.42(1.04-5.65)], hypertension [RR 6.21(3.22-11.97)], anesthetic risk II-

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Author

Virgina Durán Muñoz-Cruzado; Laura Navarro Morales; Felipe Pareja Ciuró; Daniel Aparicio Sánchez; Luis Tallón Aguilar; Javier Padillo-Ruiz

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2023

Field

Medicine (Health Sciences)