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What is Prostaglandins in Obstetric Labor about?
Prostaglandins play an important role in initiating and maintaining labor by acting as paracrine/autocrine hormones produced in the amnion, chorion, decidua, and myometrium. They trigger myometrial contractions irrespective of gestation duration, unlike oxytocin which acts predominantly during term or labor. Prostaglandin synthesis is triggered by increases in estrogen, glucocorticoids, mechanical stretching late in pregnancy, and cytokines from infection or examinations. They are synthesized from arachidon
- Author
- Harshal Chavan
- Language
- EN