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What is Mechanism of Alkylating Antineoplastics about?
Alkylating agents are a class of chemotherapy drugs that work by attaching alkyl groups to DNA, damaging its structure. This prevents cancer cells from replicating faster than healthy cells can be repaired. While effective at treating several cancer types, alkylating agents are also toxic to normal cells. They were first developed from nitrogen mustard gas in World War 1 and helped pioneer modern cancer chemotherapy. Examples include cyclophosphamide, cisplatin, and melphalan.
- Author
- Mannit Buttar
- Language
- EN