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Graftskin Treatment of Difficult to Heal Diabetic Foot Ulcers: One Center's Experience by Hunter H. Sams; June Chen; Lloyd E. King is a Medicine article available to read on EtoBox.

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## Background: Chronic diabetes-related foot ulcers result from predisposition, tissue injury, and inadequate reparative mechanisms. standard care for diabetes-related foot ulcers includes weight off-loading, pressure-relieving footwear, aggressive surgical debridement, and frequent dressing changes. graftskin is a recently developed living skin construct. ## Objective: To compare graftskin and standardized wound care to standardized wound care alone in the treatment of difficult to heal diabetes-related neuropathic foot ulcers, and to assess the handling and application characteristics of graftskin. ## Methods: A university dermatology clinic was part of a 24-center prospective, randomized, controlled, parallel group comparative trial of graftskin for the treatment of difficult to heal neuropathic diabetes-related foot ulcers. patients were randomly assigned to treatment with graftskin with aggressive debridement and standardized wound care, or aggressive debridement and standardized wound care alone. blinding was not feasible due to device visibility during application. ## Results: Five of nine patients (56%) treated with graftskin therapy had complete healing. three of eight con

Who reads Graftskin Treatment of Difficult to Heal Diabetic Foot Ulcers: One Center's Experience?

Author

Hunter H. Sams; June Chen; Lloyd E. King

Publisher

John Wiley and Sons; Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Wolters Kluwer Health; Ovid Technologies (Wolters Kluwer Health); Elsevier BV (ISSN 1076-0512)

Published

2002

Language

EN

Field

Medicine (Health Sciences)