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Acute on chronic kidney disease in dogs: Etiology, clinical and clinicopathologic findings, prognostic markers, and survival by Asia Dunaevich; Hilla Chen; Danielle Musseri; Sharon Kuzi; Michal Mazaki‐Tovi; Itamar Aroch; Gilad Segev is a Medicine article available to read on EtoBox.
What is Acute on chronic kidney disease in dogs: Etiology, clinical and clinicopathologic findings, prognostic markers, and survival about?
## Abstract ## Background Chronic kidney disease (CKD) and acute exacerbation of CKD (ACKD) are common in dogs. ## Objective To characterize the etiology, clinical and laboratory findings, and short‐ and long‐term prognosis of dogs with ACKD. ## Animals One hundred dogs with ACKD. ## Methods Medical records of dogs diagnosed with ACKD admitted to a veterinary teaching hospital were retrospectively reviewed. ## Results The most common clinical signs included anorexia (84%), lethargy (77%), vomiting (55%) and diarrhea (37%). Presumptive etiology included inflammatory causes (30%), pyelonephritis (15%), ischemic causes (7%), other (3%), or unknown (45%). Median hospitalization time was 5 days (range, 2‐29 days) and was significantly longer in survivors (6 days; range, 2‐29 days) compared with nonsurvivors (4 days; range, 2‐20 days; __P__ < .001). Mortality rate was 35%. International Renal Interest Society (IRIS) acute kidney injury (AKI) grade at presentation was associated (__P__ = .009) with short‐term survival, but presumptive etiology was not (__P__ = .46). On multivariable analysis; respiratory rate (__P__ = .01), creatine kinase (CK) activity (__P__ = .005) and serum creatinine
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- Author
- Asia Dunaevich; Hilla Chen; Danielle Musseri; Sharon Kuzi; Michal Mazaki‐Tovi; Itamar Aroch; Gilad Segev
- Publisher
- Wiley
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)