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Basic biochemical and hematological parameters of structural hemoglobin variants in the postpartum women and their respective newborn from Manaus, Amazonas, Brazil by Roberta da Silva Brito; Lecita Marreira de Lima Barros; Lilian Wallace Moreira; Regina Neves Normando; Thiago Bacha de Jesus; Marilda de Souza Gonçalves; Rajendranath Ramasawmy; Stéfani Ferreira de Oliveira; Keyla Emanulle Ramos da Silva; Nelson Abrahim Fraiji; Larissa Feitosa da Hora; Rebeca Linhares de Abreu Netto; José Pereira de Moura Neto is a Medicine article available to read on EtoBox.

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## Abstract The present study aimed at estimating the prevalence of structural hemoglobinopathies in newborn and describing the hematological and biochemical characteristics between postpartum women (PW) and their respective newborns (NB) at a public maternity hospital in Manaus, Amazonas state, Brazil. In total, 825 NB and 820 PW were included in the study. Hematological and biochemical analysis and screening of structural hemoglobinopathies were performed and compared in groups of individuals (NICU or not; hemoglobin genotypes; gestational age and prenatal). The age of PW ranged from 13 to 44 years old (mean of 23.7 ± 6.6 years), with 45.9% pregnant for the first time and 54.1% multiparous. Reported receiving prenatal care 88% and regarding the type of delivery, 47.7% had delivered by cesarean section. Among the births, 19.4% were born premature and 8.3% were admission to the neonatal intensive care unit (NICU). The male NB represented 53.4% of the total. Sickle cell trait (FAS) was found in 16 (1.94%) and heterozygous for D hemoglobin (FAD) in 6 (0.73%) newborns. A statistically significant values was found between the previous history of miscarriage and increase of Mean corpusc

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Author

Roberta da Silva Brito; Lecita Marreira de Lima Barros; Lilian Wallace Moreira; Regina Neves Normando; Thiago Bacha de Jesus; Marilda de Souza Gonçalves; Rajendranath Ramasawmy; Stéfani Ferreira de Oliveira; Keyla Emanulle Ramos da Silva; Nelson Abrahim Fraiji; Larissa Feitosa da Hora; Rebeca Linhares de Abreu Netto; José Pereira de Moura Neto

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)