Opening book details…
Can I read Preparation of Platelet-rich Plasma as a Tissue Adhesive for Experimental Transplantation in Rabbits on EtoBox?
Preparation of Platelet-rich Plasma as a Tissue Adhesive for Experimental Transplantation in Rabbits by Federico Luengo Gimeno; Silvia Gatto; José Ferro; Juan Oscar Croxatto; Juan Eduardo Gallo is a Medicine article available to read on EtoBox.
What is Preparation of Platelet-rich Plasma as a Tissue Adhesive for Experimental Transplantation in Rabbits about?
## Purpose Platelet-rich plasma (PRP) is an autologous substance with adhesive properties. We aimed at developing and testing the efficacy of a method for PRP preparation in rabbits. ## Materials and methods An __in vitro__ study was carried out to obtain PRP from forty rabbits and to analyze the number of platelets and type of substance needed to trigger platelet activation. To induce platelet activation, 5%, 10%, 25% and 50% CaCl solutions were used. Then, an __in vivo__ study was performed in twelve rabbits to test PRP adhesiveness in lamellar corneal graft. A control group made up of six rabbits underwent corneal transplantation without using PRP. ## Results 5% CaCl was the most effective concentration in activating PRP, with a mean time of 19 minutes. An attached corneal flap was seen 3 months after surgery. A detached corneal button was seen in all controls. ## Conclusion Our method was able to produce rabbit-derived PRP with suitable properties for soft tissue adhesion. These results could be useful for researchers of the growing fields of tissue repair and experimental transplantation.
Who reads Preparation of Platelet-rich Plasma as a Tissue Adhesive for Experimental Transplantation in Rabbits?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Federico Luengo Gimeno; Silvia Gatto; José Ferro; Juan Oscar Croxatto; Juan Eduardo Gallo
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2003-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1477-9560)
- Published
- 2006
- Language
- EN
- Field
- Medicine (Health Sciences)