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Toxic Epidermal Necrolysis in Acquired Immunodeficiency Syndrome Treated with Intravenous Gammaglobulin by Tri G Phan; Richard Cw Wong; Kerry Crotty; Stephen Adelstein is a Medicine article available to read on EtoBox.

What is Toxic Epidermal Necrolysis in Acquired Immunodeficiency Syndrome Treated with Intravenous Gammaglobulin about?

A 31‐year‐old man with the acquired immunodeficiency syndrome who developed toxic epidermal necrolysis (TEN) was successfully treated with intravenous immunoglobulin. He presented with a widespread, blistering skin rash, extensive mucosal ulceration, high‐grade fever and pancytopaenia. Nevirapine, a non‐nucleoside reverse transcriptase inhibitor, was suspected as the culprit drug, although the patient had been taking this medication for 6 months. The patient also demonstrated an increased number of gamma/delta (γδ) T cells that decreased concomitantly with his clinical improvement. This correlation has not been described in TEN previously and may be of pathophysiological significance.

Who reads Toxic Epidermal Necrolysis in Acquired Immunodeficiency Syndrome Treated with Intravenous Gammaglobulin?

Author

Tri G Phan; Richard Cw Wong; Kerry Crotty; Stephen Adelstein

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0004-8380)

Published

1999

Language

EN

Field

Medicine (Health Sciences)