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Total ablative stereotactic body radiotherapy to primary and oligometastatic renal cell carcinoma in medically inoperable cases: An institutional analysis by Bisht, Shyam Singh (author);Kataria, Tejinder (author);Shishak, Sorun (author);Gupta, Deepak (author);Kaliyaperumal, Venkatesan (author);Wadhwa, Jyoti (author);Suryavanshi, Manav (author);Banerjee, Susovan (author);Narang, Kushal (author);Goyal, Shina (author);Rathi, Deepak (author);Mayank, Mayur (author);Selvaraj, Rajesh (author);Khandelwal, Anubhav (author) is a Medicine article available to read on EtoBox.

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## ABSTRACT ## Introduction: Stereotactic body radiotherapy (SBRT) has been found to be an effective and safe modality with excellent oncological outcome in medically inoperable primary renal cell carcinoma (RCC) and oligometastases. There is scarcity of data on the synchronous delivery of SBRT to primary and oligometastatic RCC in patients unfit for nephrectomy. Here, we report the findings of a retrospective study of prospectively collected data on “total ablative SBRT.” ## Methods: Oligometastatic RCC patients with intact primary tumors were enrolled between May 2021 and June 2022. SBRT was synchronously delivered to the primary tumor and metastases. Demographics, treatment, oncologic outcomes, and toxicity were assessed. Kaplan–Meier estimates were generated for oncologic outcomes. The primary endpoint of this study was feasibility and tolerability. ## Results: Eleven patients were enrolled between May 2021 and June 2022. One patient died at 2 months after SBRT due to viral pneumonitis (possibly COVID pneumonia). Nine patients (82%) had metastatic disease, while 2 (18%) were stage II. The average maximal diameter of primary was 68.7 mm (range, 23–128 mm). The SBRT doses for pri

Who reads Total ablative stereotactic body radiotherapy to primary and oligometastatic renal cell carcinoma in medically inoperable cases: An institutional analysis?

Author

Bisht, Shyam Singh (author);Kataria, Tejinder (author);Shishak, Sorun (author);Gupta, Deepak (author);Kaliyaperumal, Venkatesan (author);Wadhwa, Jyoti (author);Suryavanshi, Manav (author);Banerjee, Susovan (author);Narang, Kushal (author);Goyal, Shina (author);Rathi, Deepak (author);Mayank, Mayur (author);Selvaraj, Rajesh (author);Khandelwal, Anubhav (author)

Publisher

Medknow

Published

2023

Field

Medicine (Health Sciences)