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Effects of Graded Upper Airway Obstruction on Pulmonary Mechanics During Transtracheal Jet Ventilation by M.L. Carl; K.J. Rhee; E.S. Schelegle; J.F. Green is a Medicine article available to read on EtoBox.

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Interventions: The first group (EPI) initially received a single subcutaneous dose of 0.3 mL of 1:1,000 epinephrine combined with an aerosolized updraft of 2.5 mg of albuterol in 2.5 mL of normal saline. The second group (CTR) received a single subcutaneous injection of 0.3 mL of normal saline combined with 2.5 mg of alhuterol in an aerosolized updraft. Both groups received additional doses of aerosolized albuterol at 20 and 40 minutes after the initial treatment, if clinically indmated. The FEV 1 spirometry and vital signs were measured with initial treatment and then every 30 minutes. Measurements and main results: There was no statistically significant difference in mean patient ages (26 versus 28.5 years, P = .3772), duration of asthma attack (23.4 versus 29.3 hours, P > .5), pretreatment FEV t (1.5 versus 1.4 L, P = .6229), 30-minute FEV l (2.3 versus 2.0 L, P = .1770), or 60-minute FEV I (2.7 versus 2.3 L, P = .1734) for the EPI or CTR groups, respectively. Conclttsion: Subcutaneous epinephrine provided no additional benefit to use of a ~]2-agonist by nebulization in mildly to moderately ill adult asthma patients. The simultaneous use of subcutaneous and inhaled [~2-agonist i

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Author

M.L. Carl; K.J. Rhee; E.S. Schelegle; J.F. Green

Publisher

Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV (ISSN 1097-6760)

Published

1994

Language

EN

Field

Medicine (Health Sciences)