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Evaluation of Herbal Cannabis Characteristics by Medical Users: a Randomized Trial by Mark A Ware; Thierry Ducruet; Ann R Robinson is a Medicine article available to read on EtoBox.

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## Background Cannabis, in herbal form, is widely used as self-medication by patients with diseases such as HIV/AIDS and multiple sclerosis suffering from symptoms including pain, muscle spasticity, stress and insomnia. Valid clinical studies of herbal cannabis require a product which is acceptable to patients in order to maximize adherence to study protocols. ## Methods We conducted a randomized controlled crossover trial of 4 different herbal cannabis preparations among 8 experienced and authorized cannabis users with chronic pain. Preparations were varied with respect to grind size, THC content and humidity. Subjects received each preparation on a separate day and prepared the drug in their usual way in a dedicated and licensed clinical facility. They were asked to evaluate the products based on appearance (smell, colour, humidity, grind size, ease of preparation and overall appearance) and smoking characteristics (burn rate, hotness, harshness and taste). Five-point Likert scores were assigned to each characteristic. Scores were compared between preparations using ANOVA. ## Results Seven subjects completed the study, and the product with highest THC content (12%), highest humid

Who reads Evaluation of Herbal Cannabis Characteristics by Medical Users: a Randomized Trial?

Author

Mark A Ware; Thierry Ducruet; Ann R Robinson

Publisher

BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, c2004-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1477-7517)

Published

2006

Language

EN

Field

Medicine (Health Sciences)