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Can I read Obesity Management and Chronic Kidney Disease on EtoBox?
Obesity Management and Chronic Kidney Disease by Yang Chen; Walaa Dabbas; Antonio Gangemi; Enrico Benedetti; James Lash; Patricia W. Finn; David L. Perkins is a Medicine article available to read on EtoBox.
What is Obesity Management and Chronic Kidney Disease about?
Obesity is one of the risk factors for the development and progression of chronic kidney disease (CKD). Several studies have shown the association between increased body mass index and kidney function decline. Obesity leads to CKD directly by acting as an independent risk factor and indirectly through increasing risks for diabetes, hypertension, and atherosclerosis, a group of well-established independent risk factors for CKD. Alterations in renal hemodynamics, inflammation, and in hormones and growth factors results in hyperfiltration injury and focal segmental glomerulosclerosis. In recent years, many studies have shown that the gut microbiome may play a role in the pathogenesis of obesity. Dysbiosis has been noted in obese subjects in both human and animal studies. Changes in the gut microbiome in obese patients promote weight gain by effectively extracting energy from diet, and induction of low-grade inflammation. Evidence also points to the role of inflammation within the adipose tissue in obesity as a key factor in the pathogenesis of obesityrelated complications. Thus, obesity is the net result of complex interactions between behavioral, genetic, and environmental factors. I
Who reads Obesity Management and Chronic Kidney Disease?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Yang Chen; Walaa Dabbas; Antonio Gangemi; Enrico Benedetti; James Lash; Patricia W. Finn; David L. Perkins
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)