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Glutathione Peroxidase, Selenoprotein P and Selenium in Serum of Elderly Subjects in Relation to Other Biomarkers of Nutritional Status and Food Intake by B Åkesson; W Huang; M Persson-Moschos; E Marchaluk; L Jacobsson; F Lindgärde is a Medicine article available to read on EtoBox.

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The relation of the intake of selenium and different food groups to serum levels of selenium, glutathione peroxidase and selenoprotein P, and urinary selenium was studied in 50-to 69-year-old subjects (101 men, 105 women). Blood was sampled six times during the course of 1 year, and during the same time the subjects performed six 3-day weighed dietary records. The concentration of glutathione peroxidase in serum was higher among men (4.3 (0.74) mg/L) (mean (SD)) than among women (4.0 (0.76) mg/L, P Ͻ 0.03), whereas men had lower serum selenium (1.10 (0.17) mol/L) vs. 1.17 (0.19) mol/L, P Ͻ 0.01). The intake of selenium among men was calculated to be 36 (18 -54) g/day and among women 29 (13-48) g/day (geometric means (90% central range)), but there was no significant gender difference when the selenium intake was corrected for energy intake. No difference between men and women was observed for serum selenoprotein P (1.47 (0.25) a.u. versus 1.47 (0.24) a.u. (mean(SD)) or urinary selenium excretion (0.31 (0.09) mol/d vs. 0.27 (0.08) mol/d). Serum selenium was significantly associated with selenoprotein P in both sexes but with glutathione peroxidase only in men. Serum selenium had a m

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Author

B Åkesson; W Huang; M Persson-Moschos; E Marchaluk; L Jacobsson; F Lindgärde

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0955-2863)

Published

1997

Language

EN

Field

Medicine (Health Sciences)