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What is Urine Dilution and Concentration Mechanisms about?
The kidneys have a tremendous capacity to vary the concentration of urine in response to changes in water balance. When there is excess water in the body, the kidneys can excrete very dilute urine of 50 mOsm/L, and when water is deficient, concentrated urine of 1200-1400 mOsm/L. Loops of Henle in juxtamedullary nephrons function as countercurrent multipliers to establish the hyperosmotic medullary interstitium. Vasa recta maintain this hyperosmolarity through countercurrent exchange. Antidiuretic hormone (A
- Author
- warikogatuma
- Language
- EN