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What is Bio Transformation about?
The document provides an overview of drug metabolism, emphasizing the liver as the primary site for biotransformation through enzymatic processes, particularly involving cytochrome P450 enzymes. It details the phases of drug metabolism, including Phase I (functionalization) and Phase II (conjugation), which convert lipophilic compounds into more polar, water-soluble metabolites for excretion. Additionally, it discusses various metabolic pathways and the significance of different conjugating molecules in det
- Author
- Sophia Lira Calalo
- Language
- EN