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Anti-Markovnikov Hydroboration Explained by MARÍA JESÚS VARGAS ESPINOZA is a document available to read on EtoBox.
1) Hydrogen chloride addition to propene follows Markovnikov regioselectivity, forming the more stable 2-chloropropane product, because the initial carbocation intermediate (2-propenium) that forms via the best charge match is also the most stable. 2) In contrast, hydroboration-oxidation of alkenes produces the anti-Markovnikov alcohol product. This is because the initial borane adduct intermediate that forms via best charge match (e.g. 1-boranepropane) crosses to a less stable alcohol product due to the
- Author
- MARÍA JESÚS VARGAS ESPINOZA
- Language
- EN