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The study presents SANA, a novel nitroalkene derivative of salicylate, which demonstrates significant weight loss and metabolic benefits in preclinical models of diet-induced obesity by enhancing creatine-dependent thermogenesis. SANA was found to reduce liver steatosis and insulin resistance, showing good safety and tolerability in a phase 1A/B clinical trial. This research highlights SANA
- Author
- xinlan
- Language
- EN