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Can I read Living donor liver transplantation for hepatocellular carcinoma: A single-center preliminary report on EtoBox?

Living donor liver transplantation for hepatocellular carcinoma: A single-center preliminary report by Massimo Malagó; Georgios C. Sotiropoulos; Silvio Nadalin; Camino Valentin-Gamazo; Andreas Paul; Hauke Lang; Arnold Radtke; Fuat Saner; Ernesto Molmenti; Susanne Beckebaum; Guido Gerken; Andrea Frilling; Christoph E. Broelsch is a Medicine article available to read on EtoBox.

What is Living donor liver transplantation for hepatocellular carcinoma: A single-center preliminary report about?

Liver transplantation (LT) is the treatment of choice for early hepatocellular carcinoma (HCC) in patients with end-stage liver disease but is limited by the availability of donor organs. Living donor liver transplantation (LDLT) represents an alternative therapeutic option for patients with disease confined to the liver. Between April 1998 and December 2003, 537 patients underwent liver transplantation in our center. Thirty patients with HCC and associated terminal cirrhosis and 4 patients with tumor recurrence after liver resection who underwent LDLT were reviewed. Nineteen patients (55.8%) met the Milan criteria for LT, whereas 15 patients (44.2%) "exceeded" them. The overall survival rates at 1 and 2 years were 68% and 62%, respectively, with a median follow-up of 41 months (range, 17-64 months). Five patients (14.7%) died in the first 30 days after LDLT. Hospital mortality was significantly correlated with age Ͼ60 years. Four patients developed recurrence between 6 and 35 months after LDLT. Recurrence was significantly related to the presence of more than 3 tumor lesions in our series. In conclusion, LDLT is a promising treatment option for patients with HCC. Even longer follo

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Author
Massimo Malagó; Georgios C. Sotiropoulos; Silvio Nadalin; Camino Valentin-Gamazo; Andreas Paul; Hauke Lang; Arnold Radtke; Fuat Saner; Ernesto Molmenti; Susanne Beckebaum; Guido Gerken; Andrea Frilling; Christoph E. Broelsch
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2006
Language
EN
Field
Medicine (Health Sciences)

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