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Can I read The experimental chemical hardness in the interaction between β-tubulin and epothilone B on EtoBox?
The experimental chemical hardness in the interaction between β-tubulin and epothilone B by S P Corzo; P R Bueno; D A Miranda is a Physics and Astronomy article available to read on EtoBox.
What is The experimental chemical hardness in the interaction between β-tubulin and epothilone B about?
## Abstract We showed the use of the experimental chemical hardness in the analysis of the interaction between __β__-tubulin and epothilone B. The interaction is analyzed by exposing the Epothilone B to a sensor based on an organic self-assembled monolayer functionalized with Beta tubulin. The proposed methodology is nondestructive and label-free. It allows us to compare the interaction between Beta-tubulin and different concentrations of the pharmacological molecule, __i.e__., epothilone B. The interaction is analyzed by the experimental hardness obtained according to the Miranda-Bueno methodology. We observed a linear behavior between the logarithm of the chemical hardness and the logarithm of epothilone B concentration. The results suggest the experimental chemical hardness can be used to compare the interaction of __β__-tubulin with epothilone B and with other pharmacological molecules.
Who reads The experimental chemical hardness in the interaction between β-tubulin and epothilone B?
It is typically read by researchers, students, and practitioners in Physics and Astronomy.
- Author
- S P Corzo; P R Bueno; D A Miranda
- Publisher
- Institute of Physics; IOP Publishing (ISSN 1742-6588)
- Published
- 2019
- Language
- EN
- Field
- Physics and Astronomy (Physical Sciences)