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Transcutaneous Bilirubin Accuracy Before, During, and After Phototherapy: A Meta-Analysis by Lisa ten Kate; Tiemen van Oorschot; Jessica Woolderink; Sarah Teklenburg-Roord; Jolita Bekhof is a Medicine article available to read on EtoBox.

What is Transcutaneous Bilirubin Accuracy Before, During, and After Phototherapy: A Meta-Analysis about?

## CONTEXT Transcutaneous bilirubinometry (TcB) is used as a valid screening to identify neonates requiring measurement of total serum bilirubin (TSB) before phototherapy. Its use during and after phototherapy is not advised yet because of unknown reliability. ## OBJECTIVES To determine the agreement of TcB and TSB measurements before, during, and after phototherapy. ## DATA SOURCES PubMed Medline, Cochrane Library, and references of eligible studies were searched. ## STUDY SELECTION Prospective and retrospective cohort and cross-sectional studies reporting Bland-Altman statistics of paired TcB and TSB measurements in term and preterm newborns. ## DATA EXTRACTION Meta-analysis was performed using the Mantel-Haenszel weighted approach. The agreement between TcB and TSB in μmol/L was described by pooled mean differences (MDs) and limits of agreement (LoA). ## RESULTS Fifty-four studies were included. The pooled MD before phototherapy is 2.5 μmol/L (LoA −38.3 to 43.3). The pooled MD during phototherapy is −0.3 μmol/L (LoA −34.8 to 34.2) on covered skin and −28.6 μmol/L (LoA −105.7 to 48.5) on uncovered skin. The pooled MD after phototherapy is −34.3 μmol/L (LoA −86.7 to 18.1) on cover

Who reads Transcutaneous Bilirubin Accuracy Before, During, and After Phototherapy: A Meta-Analysis?

Author

Lisa ten Kate; Tiemen van Oorschot; Jessica Woolderink; Sarah Teklenburg-Roord; Jolita Bekhof

Publisher

American Academy of Pediatrics (AAP)

Published

2023

Field

Medicine (Health Sciences)