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MAO-A vs MAO-B: Roles in Neurotransmission by Clara Lupinta Durand is a document available to read on EtoBox.
This study redefines the roles of monoamine oxidase (MAO) isoenzymes, demonstrating that MAO-A is primarily responsible for the degradation of dopamine in the striatum, while MAO-B is crucial for the synthesis of tonic GABA in astrocytes. The findings challenge the traditional belief that MAO-B significantly contributes to dopamine degradation, particularly in the context of Parkinson
- Author
- Clara Lupinta Durand
- Language
- EN