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A Myocybernetic Model of the Lower Urinary Tract by E.H.C. Bastiaanssen; J.L. van Leeuwen; J. Vanderschoot; P.A. Redert is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is A Myocybernetic Model of the Lower Urinary Tract about?

A biomechanical model of the lower urinary tract which is able to respond to input signals from a neural network is presented. The neural input is the starting point in the description of the relationships between the various physical parameters in the mechanical model of the bladder and the urethra. The cybernetics of the lower urinary tract are described on the basis of the muscle dynamics of simple models of both the detrusor in the bladder wall and the urethral sphincter. The urethral sphincter is not described as a variable resistance, like in other biomechanical models of the lower urinary tract, but is described on the basis of striated muscle dynamics. The forces produced by the detrusor and the urethral sphincter give rise to the bladder pressure and the urethral pressure. Using quasi-steady assumptions, the flow rate of urine is calculated as a result of the pressure difference between the bladder and the urethra. Parameters like the bladder volume, the flow rate and the pressure in the bladder can be compared with clinical data of urodynamic measurements. Simulation results show that the model is able to mimic both a filling and an emptying behaviour which resembles the

Who reads A Myocybernetic Model of the Lower Urinary Tract?

Author

E.H.C. Bastiaanssen; J.L. van Leeuwen; J. Vanderschoot; P.A. Redert

Publisher

Elsevier Science; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 0022-5193)

Published

1996

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)