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Can I read Towards the Molecular Era of Discriminating Multiple Lung Cancers on EtoBox?
Towards the Molecular Era of Discriminating Multiple Lung Cancers by Ziyang Wang; Xiaoqiu Yuan; Guanchao Jiang; Yun Li; Fan Yang; Jun Wang; Kezhong Chen is a Medicine article available to read on EtoBox.
What is Towards the Molecular Era of Discriminating Multiple Lung Cancers about?
## Summary In the era of histopathology-based diagnosis, the discrimination between multiple lung cancers (MLCs) poses significant uncertainties and has thus become a clinical dilemma. However, recent significant advances and increased application of molecular technologies in clonal relatedness assessment have led to more precision in distinguishing between multiple primary lung cancers (MPLCs) and intrapulmonary metastasis (IPMs). This review summarizes recent advances in the molecular identification of MLCs and compares various methods based on somatic mutations, chromosome alterations, microRNAs, and tumor microenvironment markers. The paper also discusses current challenges at the forefront of genomics-based discrimination, including the selection of detection technology, application of next-generation sequencing, and intratumoral heterogeneity (ITH). In summary, this paper highlights an entrance into the primary stage of molecule-based diagnostics.
Who reads Towards the Molecular Era of Discriminating Multiple Lung Cancers?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ziyang Wang; Xiaoqiu Yuan; Guanchao Jiang; Yun Li; Fan Yang; Jun Wang; Kezhong Chen
- Publisher
- Elsevier
- Published
- 2023
- Language
- EN
- Field
- Medicine (Life Sciences)