About this document

Mitochondria Transfer Enhances Glioblastoma by petrichorny2 is a document available to read on EtoBox.

This study reveals that mitochondria transfer from astrocytes to glioblastoma (GBM) cells enhances tumorigenicity, driven by intercellular connections facilitated by growth-associated protein 43 (GAP43). The transfer increases mitochondrial respiration and promotes cell cycle progression, leading to enhanced proliferation and self-renewal of GBM cells. These findings highlight a critical host-tumor interaction that could inform therapeutic strategies for GBM.

Author

petrichorny2

Language

EN