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Discovery and distribution of super‐integrons among Pseudomonads by Romualdas Vaisvila; Richard D. Morgan; Janos Posfai; Elisabeth A. Raleigh is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Discovery and distribution of super‐integrons among Pseudomonads about?

Until recently, integrons (systems for acquisition and expression of new genetic materials) have been associated generally with antibiotic resistance gene cassettes. The discovery of ‘super‐integrons’ in __Vibrionaceae__ suggests a greater impact of this gene acquisition mechanism on bacterial genome evolution than initially believed. Super‐integrons may contain more than 100 gene cassettes and may encode other determinants, including biochemical functions or virulence factors. Here, we report the genetic organization of a super‐integron from __Pseudomonas alcaligenes__ ATCC 55044. This is the first evidence of a super‐integron in a non‐pathogenic bacterium, one which is widely distributed in a great number of ecological niches such as soil and aquatic habitats. Here, the sequence composition, open reading frame (ORF) content and organization of In55044 are described and found to have features intermediate between the multidrug‐resistant integrons and the __Vibrio cholerae__ super‐integron. Similar structures are inferred to be present in several __Pseudomonas__ species, based on polymerase chain reaction (PCR) experiments.

Who reads Discovery and distribution of super‐integrons among Pseudomonads?

Author

Romualdas Vaisvila; Richard D. Morgan; Janos Posfai; Elisabeth A. Raleigh

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0950-382X)

Published

2001

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)