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Can I read Rhodium-catalyzed Intramolecular Conjugate Addition of Vinylstannanes to Dihydro-4-pyridones: a Simple Method for Stereoselective Construction of 1-Azabicyclic Alkaloids on EtoBox?
Rhodium-catalyzed Intramolecular Conjugate Addition of Vinylstannanes to Dihydro-4-pyridones: a Simple Method for Stereoselective Construction of 1-Azabicyclic Alkaloids by Bartłomiej Furman; Grzegorz Lipner is a Chemistry article available to read on EtoBox.
What is Rhodium-catalyzed Intramolecular Conjugate Addition of Vinylstannanes to Dihydro-4-pyridones: a Simple Method for Stereoselective Construction of 1-Azabicyclic Alkaloids about?
A straightforward route for the stereoselective synthesis of unsaturated quinolizidines and related higher homologs has been developed. Our results revealed that the rhodium complex [RhCl(cod)] 2 is an effective catalyst for the intramolecular conjugate addition of vinylstannanes to the dihydropyridones leading to the corresponding 1-azabicyclo[m.n.0]alkenes in a moderate to good yield and an excellent diastereoselectivity under neutral conditions at room temperature. This methodology has been successfully applied to the stereoselective synthesis of the racemic lasubine I.
Who reads Rhodium-catalyzed Intramolecular Conjugate Addition of Vinylstannanes to Dihydro-4-pyridones: a Simple Method for Stereoselective Construction of 1-Azabicyclic Alkaloids?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Bartłomiej Furman; Grzegorz Lipner
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)
- Published
- 2008
- Language
- EN
- Field
- Chemistry (Physical Sciences)