Can I read Osteogenic and antibacterial surfaces on additively manufactured porous Ti-6Al-4V implants: Combining silver nanoparticles with hydrothermally synthesized HA nanocrystals on EtoBox?

Osteogenic and antibacterial surfaces on additively manufactured porous Ti-6Al-4V implants: Combining silver nanoparticles with hydrothermally synthesized HA nanocrystals by Fazel, Mohammad; Salimijazi, Hamid R.; Shamanian, Morteza; Minneboo, Michelle; Modaresifar, Khashayar; van Hengel, Ingmar A.J.; Fratila-Apachitei, Lidy E.; Apachitei, Iulian; Zadpoor, Amir A. is a Engineering article available to read on EtoBox.

What is Osteogenic and antibacterial surfaces on additively manufactured porous Ti-6Al-4V implants: Combining silver nanoparticles with hydrothermally synthesized HA nanocrystals about?

The recently developed additively manufacturing techniques have enabled the fabrication of porous biomaterials that mimic the characteristics of the native bone, thereby avoiding stress shielding and facilitating bony ingrowth. However, aseptic loosening and bacterial infection, as the leading causes of implant failure, need to be further addressed through surface biofunctionalization. Here, we used a combination of (1) plasma electrolytic oxidation (PEO) using Ca-, P-, and silver nanoparticle-rich electrolytes and (2) post-PEO hydrothermal treatments (HT) to furnish additively manufactured Ti-6Al-4V porous implants with a multi-functional surface. The applied HT led to the formation of hydroxyapatite (HA) nanocrystals throughout the oxide layer. This process was controlled by the supersaturation of Ca and PO during the hydrothermal process. Initially, the high local supersaturation resulted in homogenous nucleation of spindle-like nanocrystals throughout the surface. As the process continued, the depletion of reactant ions in the outermost surface layer led to a remarkable decrease in the supersaturation degrees. High aspect-ratio nanorods and hexagonal nanopillars were, therefore

Who reads Osteogenic and antibacterial surfaces on additively manufactured porous Ti-6Al-4V implants: Combining silver nanoparticles with hydrothermally synthesized HA nanocrystals?

Author

Fazel, Mohammad; Salimijazi, Hamid R.; Shamanian, Morteza; Minneboo, Michelle; Modaresifar, Khashayar; van Hengel, Ingmar A.J.; Fratila-Apachitei, Lidy E.; Apachitei, Iulian; Zadpoor, Amir A.

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0928-4931)

Published

2021

Language

EN

Field

Engineering (Physical Sciences)