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Molecular and epidemiological features of norovirus-associated gastroenteritis outbreaks in Victoria, Australia in 2001 by John A. Marshall; Anna Dimitriadis; Peter J. Wright is a Medicine article available to read on EtoBox.

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## Abstract Norovirus was identified in 30 of 59 gastroenteritis outbreaks occurring in the state of Victoria, Australia in 2001 by RT‐PCR and/or electron microscopy (EM). Norovirus outbreaks occurred in hostels/nursing homes (27%), hospitals (13%), youth refuges (3%), social gatherings associated with food consumption (27%), school outings/camps (13%), and pre‐school/child‐minding centers (17%). Norovirus outbreaks tended to occur in the warmer months. Phylogenetic analysis identified six clusters, one within genogroup 1 (G1) and five within genogroup 2 (G2). Cluster 1, which incorporates the G2 Camberwell/Lordsdale strains, was the most common (39% of outbreaks). In 2 of 27 outbreaks, strains from two G2 clusters, 1 and 5, occurred. Norovirus G2 was more common in the young and very old than in those in intermediate years. Norovirus G2 detection rate was higher in females than in males for adults (>15 years) and the susceptibility of adult females to norovirus G2 infection relative to males increased with age. In one outbreak analyzed, some sequences had a single base substitution, but this did not result in an amino acid (aa) change. The two most common norovirus clusters (G2 cl

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Author
John A. Marshall; Anna Dimitriadis; Peter J. Wright
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0146-6615)
Published
2004
Language
EN
Field
Medicine (Health Sciences)

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