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What is Ferulic Acid about?
Ferulic acid suppresses osteoclast differentiation and bone erosion by inhibiting the RANKL-dependent NF-κB signaling pathway. The study found that ferulic acid reduced osteoclast formation, bone resorption pit area, and expression of genes related to osteoclast differentiation in a concentration-dependent manner. This suggests that ferulic acid has potential as a therapeutic for diseases involving bone loss like osteoporosis and rheumatoid arthritis.
- Author
- PradhyumKhandelwal
- Language
- EN